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Results for "

immune component

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (2) Complement System (2) DGK (1) Endogenous Metabolite (16) Eukaryotic Initiation Factor (eIF) (1) Integrin (1) Interleukin Related (2) Isotope-Labeled Compounds (5) Liposome (1) PROTAC Linkers (1)
By Research Areas:	Cancer (8) Infection (3) Inflammation/Immunology (20) Metabolic Disease (12) Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145429

IL-17A modulator-2	Interleukin Related	Neurological Disease Inflammation/Immunology Cancer
IL-17A modulator-2 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 27. IL-17A modulator-2 inhibits the biological action of IL-17A with a pIC₅₀ of 8.3. IL-17A modulator-2 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders .

HY-P3502

Zilucoplan RA101495; RA3193	Complement System	Inflammation/Immunology
Zilucoplan (RA101495), a 15-amino acid macrocyclic peptide, is a potent *complement component* 5 (C5)** inhibitor. Zilucoplan can be used in research of immune-mediated necrotising myopathy (IMNM) .

HY-W087988

3-Pentanol	Bacterial	Infection
3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .

HY-124040

BI-1950	Integrin	Inflammation/Immunology
BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor. LFA-1 is an essential component in normal immune system function and a target for agent discovery .

HY-P3502A

Zilucoplan TFA RA101495 TFA; RA3193 TFA	Complement System	Inflammation/Immunology
Zilucoplan TFA (RA101495), a 15-amino acid macrocyclic peptide, is a potent *complement component* 5 (C5)** inhibitor. Zilucoplan TFA can be used in research of immune-mediated necrotising myopathy (IMNM) .

HY-B2176

ATP Maximum Cited Publications 55 Publications Verification Adenosine 5'-triphosphate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation .

HY-W010735

ATP disodium salt hydrate 50+ Cited Publications Adenosine 5'-triphosphate disodium salt hydrate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .

HY-B0345A

ATP disodium salt 50+ Cited Publications Adenosine 5'-triphosphate disodium salt; Disodium adenosine triphosphate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .

HY-B2176B

ATP dimagnesium Maximum Cited Publications 55 Publications Verification Adenosine 5'-triphosphate dimagnesium	Endogenous Metabolite	Inflammation/Immunology
ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation .

HY-B2176C

ATP dipotassium Adenosine 5'-triphosphate dipotassium	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a central component of energy storage and metabolism in vivo. ATP dipotassium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dipotassium is an important endogenous signaling molecule in immunity and inflammation .

HY-B2176D

ATP ditromethamine Adenosine 5'-triphosphate ditromethamine	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP ditromethamine (Adenosine 5'-triphosphate ditromethamine) is a central component of energy storage and metabolism in vivo. ATP ditromethamine provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP ditromethamine is an important endogenous signaling molecule in immunity and inflammation .

HY-145240

eIF4E-IN-1	Eukaryotic Initiation Factor (eIF)	Infection Cancer
eIF4E-IN-1 is a potent inhibitor of eIF4E. eIF4E-IN-1 inhibits immunosuppression components such as immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immune suppression in certain diseases, such as cancer and infectious disease (extracted from patent WO2021003194A1, compound Y) .

HY-109506

DPPC 3 Publications Verification 129Y83	Liposome Endogenous Metabolite	Others
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-145249

ATP-PEG8-Biotin	PROTAC Linkers	Inflammation/Immunology
ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation .

HY-B2176A

ATP disodium trihydrate Maximum Cited Publications 55 Publications Verification Adenosine-5'-triphosphate disodium trihydrate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .

HY-W087988S

3-Pentanol-d5	Bacterial	Infection
3-Pentanol-d₅ is the deuterium labeled 3-Pentanol[1]. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants[2].

HY-156574

DGKζ-IN-4	DGK	Cancer
DGKζ-IN-4 is a DGK-zeta inhibitor. DGKζ-IN-4 can be used as an active component of pharmaceutical compositions. DGKζ-IN-4 is used to treat cancers associated with immune cell activation or cancers resistant to anti-PD-1 antibody/anti-PD-11 antibody treatment .

HY-B0345AS

ATP-18O4 disodium salt	Endogenous Metabolite
ATP- ¹⁸O₄ (disodium salt) is the ¹⁸O labeled ATP disodium salt[1]. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation[2][3].

HY-B2176S

ATP-13C10,15N5 Adenosine 5'-triphosphate-¹³C₁₀,¹⁵N₅	Endogenous Metabolite
ATP- ¹³C₁₀, ¹⁵N₅ is the ¹³C and ¹⁵N labeled ATP[1]. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[2][3].

HY-B2176S2

ATP-13C dilithium Adenosine 5'-triphosphate-¹³C dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP- ¹³C (Adenosine 5'-triphosphate- ¹³C) dilithium is ¹³C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-B2176S4

ATP-d14 dilithium Adenosine 5'-triphosphate-d₁₄ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP-d₁₄ (Adenosine 5'-triphosphate-d₁₄) dilithium is deuterium labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-B2176S6

ATP-13C10 dilithium Adenosine 5'-triphosphate-¹³C₁₀ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP- ¹³C₁₀ (Adenosine 5'-triphosphate- ¹³C₁₀) dilithium is ¹³C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-B2176S5

ATP-15N5 dilithium Adenosine 5'-triphosphate-¹⁵N₅ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP- ¹⁵N₅ (Adenosine 5'-triphosphate- ¹⁵N₅) dilithium is ¹⁵N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-B2176S1

ATP-13C10,15N5 disodium Adenosine 5'-triphosphate-¹³C₁₀,¹⁵N₅ disodium	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP- ¹³C₁₀, ¹⁵N₅ (disodium) is a ¹³C-labeled and ¹⁵N-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2][3][4].

HY-B2176S3

ATP-15N5,d14 dilithium Adenosine 5'-triphosphate-¹⁵N₅,d₁₄ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
ATP- ¹⁵N₅,d₁₄ (Adenosine 5'-triphosphate- ¹⁵N₅,d₁₄) dilithium is deuterium and ¹⁵N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-145430

IL-17A modulator-1	Interleukin Related	Neurological Disease Inflammation/Immunology Cancer
IL-17A modulator-1 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 9. IL-17A modulator-1 inhibits the biological action of IL-17A with a pIC₅₀ of 8.2. IL-17A modulator-1 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders .

Cat. No.	Product Name

HY-L174

Macrophage Related Compound Library	153 compounds
Macrophages are effector cells of the innate immune system, engulfing bacteria and secreting pro-inflammatory and antibacterial mediators. They are an important component of the first line defense against pathogens and tumor cells. In addition, macrophages play an important role in eliminating damaged cells through programmed cell death. Like all immune cells, macrophages originate from pluripotent hematopoietic stem cells in the bone marrow. Macrophages play key functions in many physiological processes beyond homeostasis and innate immunity, including metabolic function, cell debris clearance, tissue repair, and remodeling. In order to fulfill their different functional roles, macrophages can polarize into a series of phenotypes, including classic (pro inflammatory, M1) and alternative (anti-inflammatory, healing promoting, M2) activation states, as well as a wide range of regulatory phenotypes and subtypes. Macrophages exist in all vertebrate tissues and have a dual function in host protection and tissue damage, maintaining a good balance. MCE designs a unique collection of 153 macrophage related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

Macrophage Related Compound Library

153 compounds

Macrophages are effector cells of the innate immune system, engulfing bacteria and secreting pro-inflammatory and antibacterial mediators. They are an important component of the first line defense against pathogens and tumor cells. In addition, macrophages play an important role in eliminating damaged cells through programmed cell death. Like all immune cells, macrophages originate from pluripotent hematopoietic stem cells in the bone marrow. Macrophages play key functions in many physiological processes beyond homeostasis and innate immunity, including metabolic function, cell debris clearance, tissue repair, and remodeling. In order to fulfill their different functional roles, macrophages can polarize into a series of phenotypes, including classic (pro inflammatory, M1) and alternative (anti-inflammatory, healing promoting, M2) activation states, as well as a wide range of regulatory phenotypes and subtypes. Macrophages exist in all vertebrate tissues and have a dual function in host protection and tissue damage, maintaining a good balance.

MCE designs a unique collection of 153 macrophage related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

HY-L132

Chemokine Compound Library	146 compounds
Chemokines, or chemotactic cytokines, are small cytokines or signaling proteins secreted by cells. They are a component of intercellular communication, controlling the directional movement of immune cells especially leukocytes, as well as other cell types, for instance, endothelial and epithelial cells, which are essential to maintain human health and the function of the immune system. The biological effects of chemokines are achieved by binding to chemokine receptors, which are G protein-coupled receptors found on the surface of leukocytes. Some chemokine receptors are involved in directing tumor metastasis and over-expression by certain tumors. So inhibiting the interaction between chemokine and chemokine receptors on the surface of tumor cells may be a new possible therapeutic approach. Some chemokine receptors are coreceptors for HIV entry, and related inhibitors have been approved by the FDA to treat patients with HIV. Obviously, chemokines and chemokine receptors have become new targets for studying cancer, HIV, inflammation, and other diseases. MCE supplies a unique collection of 146 chemokine or chemokine receptor inhibitors and activators, all of which have the identified inhibitory or activated effect on chemokine or chemokine receptors. MCE Chemokine Library is a useful tool for drug research related to cancer, AIDS, and wound therapy.

Chemokine Compound Library

146 compounds

Chemokines, or chemotactic cytokines, are small cytokines or signaling proteins secreted by cells. They are a component of intercellular communication, controlling the directional movement of immune cells especially leukocytes, as well as other cell types, for instance, endothelial and epithelial cells, which are essential to maintain human health and the function of the immune system.

The biological effects of chemokines are achieved by binding to chemokine receptors, which are G protein-coupled receptors found on the surface of leukocytes. Some chemokine receptors are involved in directing tumor metastasis and over-expression by certain tumors. So inhibiting the interaction between chemokine and chemokine receptors on the surface of tumor cells may be a new possible therapeutic approach. Some chemokine receptors are coreceptors for HIV entry, and related inhibitors have been approved by the FDA to treat patients with HIV. Obviously, chemokines and chemokine receptors have become new targets for studying cancer, HIV, inflammation, and other diseases.

MCE supplies a unique collection of 146 chemokine or chemokine receptor inhibitors and activators, all of which have the identified inhibitory or activated effect on chemokine or chemokine receptors. MCE Chemokine Library is a useful tool for drug research related to cancer, AIDS, and wound therapy.

ATP dimagnesium 50+ Cited Publications Adenosine 5'-triphosphate dimagnesium	Biochemical Assay Reagents
ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation .

DPPC 3 Publications Verification 129Y83	Drug Delivery
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

Cobra Venom Factor CVF	Native Proteins
Cobra venom factor (CVF) is the complement-activating protein from cobra venom. CVF is a three-chain protein that functionally resembles C3b, the activated form of complement component C3. Cobra Venom Factor can be used for the research of the functions of complement in host defense and immune response as well as in the pathogenesis of diseases .

Zilucoplan RA101495; RA3193	Complement System	Inflammation/Immunology
Zilucoplan (RA101495), a 15-amino acid macrocyclic peptide, is a potent *complement component* 5 (C5)** inhibitor. Zilucoplan can be used in research of immune-mediated necrotising myopathy (IMNM) .

Zilucoplan TFA RA101495 TFA; RA3193 TFA	Complement System	Inflammation/Immunology
Zilucoplan TFA (RA101495), a 15-amino acid macrocyclic peptide, is a potent *complement component* 5 (C5)** inhibitor. Zilucoplan TFA can be used in research of immune-mediated necrotising myopathy (IMNM) .

Cat. No.	Product Name	Category	Target	Chemical Structure